The enzyme pattern of the people are different, so an accurate analysis wise to carry out a targeted consultation.
important is the portion of glutathione S-transferases (GST) if this is present in too small amounts are then you are a candidate of the essential green tea to drink. But if you have high enzyme activities you should avoid him more.
glutathione S-transferases (GST) are a family of enzymes with broad substrate specificity, which play an important role in the detoxification and excretion of exogenous and endogenous Carcinogens play. To transfer the body's glutathione on many electrophilic substances, which are thus inactivated and subsequently largely eliminated by the kidneys as mercapturic acids. GST detoxify biocides, polycyclic aromatic hydrocarbons, ethylene glycols, PCBs, aflatoxins and other xenobiotics.
A potential mechanism in cancer prevention is the induction of endogenous protective systems, which include glutathione S-transferases (GST) as an important phase II enzymes. In the present study, the effect of short-chain fatty acids and phytochemicals with anticarcinogenic potential on the expression and activity of the cytosolic GSTs investigated in the colon. As the basis for studies of the GST status in the colon tissue was determined in 15 patients. The experiments for the induction, which were performed in cell models (Kolontumorzelllinien, primary Kolonfibroblastenkulturen) showed that the GSTs by butyrate and green tea extract are inducible. The final studies on the functional consequences of increased GST status showed a significantly reduced genotoxicity of 4-hydroxy-2-nonenal in cells with induced GST, which can be attributed to the stimulation of the detoxification capacity of GST.
U.S. researchers at the Arizona Cancer Center http://www.azcc.arizona.edu and the Division of Cancer Prevention at the National Cancer Institute in Bethesda http://www.cancer.gov the "health secret" of green tea a step closer. Therefore helps the tannins contained in tea catechin in detoxifying the body - and that could be one reason why it protects against cancer, the scientists report in the latest issue of the journal Cancer Epidemiology.
In the recent investigation, the researchers H.-H. Sherry Crow on a specific group of proteins called glutathione S-transferases (GST) is concentrated. GST are a family of enzymes with broad substrate specificity, which play an important role in the detoxification and excretion of carcinogenic substances. GST detoxify biocides, polycyclic aromatic hydrocarbons, ethylene glycols, PCBs, aflatoxins and other xenobiotics. In previous studies, the researchers could see that people with low GST activity have a higher cancer risk.
there a reduction of GST levels in the blood of tea consumption, the scientists could measure the basis of the 42 healthy volunteers. First, the subjects were allowed to drink over a period of four weeks no tea. Then their GST values were measured again in the blood. After this examination, they received daily on an empty stomach one capsule with green tea extracts. This product contains 800 milligrams of epigallocatechin gallate (EGCG) - A catechin, which belongs to the sub-group of polyphenols. This amount corresponds roughly to the 8:00 to 4:00 p.m. dose cups of green tea.
The blood tests showed the subjects after taking the Teekapseln to a higher average GST value. This was true also for the detoxification enzymes. What the researchers noticed was that there were large differences between the participants. Especially those subjects who had prior to the examination showed a low enzyme activity, after Teekapsel cure was higher by up to 80 percent activity. Other hand, showed that subjects in which there have an inherently high enzyme activity was a reduction of up to 20 percent. "We conclude that a dose by ECGC has a significantly different effect on the GST activity. This suggests to us that green tea capsules that people who have innately low GST levels in the blood, may protect against cancer-causing substances, "the researchers write.
The health benefits of green tea has been known for years. A Japanese study of 40,000 adults over a period of eleven years, made it clear that the beverage positively to the heart and prolong life has
glutathione S-transferases (GST) are a family of enzymes with broad substrate specificity, which play an important role in the detoxification and excretion of exogenous and endogenous Carcinogens play. To transfer the body's glutathione on many electrophilic substances, which are thus inactivated and subsequently largely eliminated by the kidneys as mercapturic acids. GST detoxify biocides, polycyclic aromatic hydrocarbons, ethylene glycols, PCBs, aflatoxins and other xenobiotics.
A potential mechanism in cancer prevention is the induction of endogenous protective systems, which include glutathione S-transferases (GST) as an important phase II enzymes. In the present study, the effect of short-chain fatty acids and phytochemicals with anticarcinogenic potential on the expression and activity of the cytosolic GSTs investigated in the colon. As the basis for studies of the GST status in the colon tissue was determined in 15 patients. The experiments for the induction, which were performed in cell models (Kolontumorzelllinien, primary Kolonfibroblastenkulturen) showed that the GSTs by butyrate and green tea extract are inducible. The final studies on the functional consequences of increased GST status showed a significantly reduced genotoxicity of 4-hydroxy-2-nonenal in cells with induced GST, which can be attributed to the stimulation of the detoxification capacity of GST.
U.S. researchers at the Arizona Cancer Center http://www.azcc.arizona.edu and the Division of Cancer Prevention at the National Cancer Institute in Bethesda http://www.cancer.gov the "health secret" of green tea a step closer. Therefore helps the tannins contained in tea catechin in detoxifying the body - and that could be one reason why it protects against cancer, the scientists report in the latest issue of the journal Cancer Epidemiology.
In the recent investigation, the researchers H.-H. Sherry Crow on a specific group of proteins called glutathione S-transferases (GST) is concentrated. GST are a family of enzymes with broad substrate specificity, which play an important role in the detoxification and excretion of carcinogenic substances. GST detoxify biocides, polycyclic aromatic hydrocarbons, ethylene glycols, PCBs, aflatoxins and other xenobiotics. In previous studies, the researchers could see that people with low GST activity have a higher cancer risk.
there a reduction of GST levels in the blood of tea consumption, the scientists could measure the basis of the 42 healthy volunteers. First, the subjects were allowed to drink over a period of four weeks no tea. Then their GST values were measured again in the blood. After this examination, they received daily on an empty stomach one capsule with green tea extracts. This product contains 800 milligrams of epigallocatechin gallate (EGCG) - A catechin, which belongs to the sub-group of polyphenols. This amount corresponds roughly to the 8:00 to 4:00 p.m. dose cups of green tea.
The blood tests showed the subjects after taking the Teekapseln to a higher average GST value. This was true also for the detoxification enzymes. What the researchers noticed was that there were large differences between the participants. Especially those subjects who had prior to the examination showed a low enzyme activity, after Teekapsel cure was higher by up to 80 percent activity. Other hand, showed that subjects in which there have an inherently high enzyme activity was a reduction of up to 20 percent. "We conclude that a dose by ECGC has a significantly different effect on the GST activity. This suggests to us that green tea capsules that people who have innately low GST levels in the blood, may protect against cancer-causing substances, "the researchers write.
The health benefits of green tea has been known for years. A Japanese study of 40,000 adults over a period of eleven years, made it clear that the beverage positively to the heart and prolong life has
Wolfgang Conzelmann
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skills practice for sustainable medicine
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